Jan 272010

Have we become a world where something is better than nothing? Are we really getting excited about the new oral treatments for Multiple Sclerosis (decent editorial overview ). Basically the same treatment repackaged in pill form. Except these drugs have worse side-effects. While Tysabri was never my cup of tea at least it was significantly more effective.

We are now left with the knowledge that the drug companies are more than willing to make designer drugs because peoples’ biggest desire is drug administration over drug effectiveness. Ask and you shall receive. Are our desires really this base.

  6 Responses to “This is Progress?”

  1. Drug companies are not interested in cures – they are interested in masking and dealing with symptoms. Take a good look at pretty much all the drugs on the market today and most of them they cant even explain the mechanism of action.

    I would have serious doubts about using a drug that the drug companies themselves cant tell you how or why it works.

    Another interesting thing I’ve read is that the “placebo effect” has been beating promising new “drugs” in clinical trials and the drug companies are stumped.

  2. Brian,
    While I did not post that I agree. Money is not made in cures only in treatments. MS and many other chronic ailments are cash cows. Why pursue a cure.

    The bottom line in until we, as a people, expect and demand more there will not be cures. I think we have the brains and the know-how it is just not being properly focused. We have to blame ourselves for being complacent.

  3. Hi Erik,
    It is good to see that you are still existing in the blogosphere. Many of us have grown tired of the format opting for Facebook instead which is more like a playhouse than serious talk. I am getting ready to walk the walk and thought I’d see what all my other cohorts were up to. I would like to get that ‘Dune Sea Garrison’ up here in Cincinnati, eh. It’s pretty cool this time of year round here. I hope that your ‘Optimism Fail’ is more to do with the progress of available treatments, than with your own coping mechanisms.
    Go Well

  4. I recently encountered a lady at a party two nights ago, who has advanced MS and we started talking about her condition. I had frankly never encountered someone with MS close up. She has significant systemic damage, effecting mostly her right side with very obvious degeneration and discoloration in her right arm and leg, compromised mobility in general, and mostly wheel chair bound, but a super attitude.

    She was delightful and open to me asking her all kinds of questions. Has she been checked for heavy metals? (Yes, no problem), Have you been taking B-compex vitamins to promote nerve health?, (Yes, for some time now.) Have you ever had massive antibiotic therapy to rule out bacterial pathogens? (No, what’s that?) When was the last time you had any form of antibiotics? (About four months ago, I had a sinus infection)… and a few other questions.

    I had exhausted my battery of questions when she interestingly cited a time when she would put on a watch and the watch would stop and sometimes run backwards. When she removed the watch, it would go back to working correctly. So this raised a number of issues regarding magnetics, iron levels, uric acid levels and the blood-brain barrier.

    MS patients typically have elevated iron levels and low uric acid levels.
    What causes the low uric acid levels?

    What causes high iron levels? Does high iron lead to a renal imbalance? Does excess iron overrun things?

    Most MS patients live far away from the equator. In the past, science suggested the geographical location meant lower sunlight and reduced Vitamin D, and perhaps its true, but what if it also means a difference in magnetics causing a compromise to the blood-brain barrier?

    To what extent does uric acid have a role in maintaining, or perhaps “tightening up”, the blood brain barrier? Could the lack of uric acid could cause the barrier to “loosen”?

    Elevated iron (which is also associated with MS) has to alter the magnetics of the brain. Does elevated iron predispose the entry of T-Cells? Is it because of the low uric acid that the iron is allowed to build up? What causes the build up of too much Iron? What accounts for the low uric acid. What normally expels excess iron? On a renal level, does the low uric acid alone cause the loosening of the barrier? What role does Vitamin B12 play in blood brain barrier features? What about Lipoic acid?

    My curiosity is centered on the blood-brain barrier, the electrical charge, and the effect of magnetics. What if, in MS, the low urea, high iron creates a charge that drags things in the wrong direction, or allows the passage (through a break) of things normally excluded? Clear evidence suggests that the entry of T Cells through a “broken” portion of the blood-brain barrier brings about the destruction of myelin which protects the nerves.

    The health of the vasculature is important for so many reasons, but the lining of vessels at the blood-brain level is critical. Inflammation of the lining could cause a break. Sugar, high spike carbs are probably very bad relative to epithelium and MS. Lipoic acid is said to improve the lining. Is excess iron an irritant?

    I want to know more about the electrical characteristics of the blood-brain barrier and what constitutes “normal” actions. What would alter these normal actions across the membrane?

  5. I just published a book called, “The Downside of Upright Posture – The Anatomical Causes of Alzheimer’s, Parkinson’s and Multiple Sclerosis.” The reviews by leading experts and scientists in science, medicine and chiropractic have been terrific. You are probably aware of the excitement caused by Dr. Zamboni using venous stents to cure MS which he attributes to “chronic cerebrospinal venous insufficiency.” It is precisely what the book is about and I have been writing about drainage issues in the brain since 1987. The latest upright PC MR angiograms are confirming my suspicions. Please visit my website at uprightdoc.com to learn more. I would appreciate your thoughts. I have spent decades investigating these neurodegenerative diseases.

  6. Very interesting reading here. I have been recently diagnosed with MS, symptoms are just electrical in nature throughout my body and I cannot handle fluorescent lights in places like Wal-Mart – I had optic neuritis in my right eye, but so far the eyesight has not returned – only about 60% – 2 lesions were found on the first brain MRI, I’m seeing a neurologist tomorrow to discuss findings on the MRI taken last Thursday. I would appreciate anyones thoughts on how to proceed – as I’m uncertain as to what drugs/therapies to start.
    Boise Bob

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