The new LLMD prescribed 3000mcg of injectable B12 twice a week to help with the fatigue. I mentioned to him that I had been taking a B100 vitamin. He said that the B12 did not absorb well through the intestines; which I had heard before (but I figured it absorbed some, and it helped, so it was better than nothing, and no one was offing IM B12). Regardless, while I was tired of the fatigue I also was not looking forward to taking a new injection; and the Rebif was at least subcutaneous. An intramuscular injection, in my mind, equated to the tetanus shots that I used to get as a child, which would hurt for a long time. Eventually, I gave myself the injection and a few hours later felt massively better. Better than I have felt in a very long time. The injection also went very well; the first time. Unfortunately, the second time I did the injection it went badly, and I can only assume I did something wrong (at least I hope the tetanus shot pain is not normal). Maybe if I had gotten some B12/IM injection training I would be better (or had been taking Avonex ;-). I did take the second injection in the evening (last night), but today I am once again feeling great, and no nasty side-effects like the Provigil gives me.