I started having significant pain (Level >7) in my right-toe shortly after starting the Levaquin. I’d had the problem before and thought this was just a sign that the Levaquin was doing its job. Unfortunately, on going to the doctor he said that it is not Lyme, but Gout. I was in disbelief for a while that I have one more problem; but with the area being red and swollen it seemed to make sense. Interestingly I had let myself run out of B100, and had not taken one in a couple of weeks. Now I wonder if my body requires the B100 to control the uric acid. Between the Hydrocodone for pain and the 500mg of Naproxen for the swelling I was doing better pretty quickly. Most interesting is that the Gout explains all of the joint pain meaning the Lyme has hit me 100% neurologically. So far the B100 and Vitamin C I take seem to help with the Gout, hopefully it can be controlled with those, a better diet, and drinking more.