As I started the antidepressants again it made both of us think back on the turning point to identify a cause. It is very clear that the depression began immediately after taking the Solu-Medrol (or while on it). Looking back on my history of depression it always immediately follows a round of Solu-Medrol, and the family consensus is that there is a definite link between the two. My theory is that, for whatever reason, it takes my body to an extremely bad place and that it takes a while to recover. I guess I’ll have to wait until this episode clears up and check again at some future round of Solu-Medrol. In the minimum I find it very bizarre that I was in excellent spirits immediately before the Solu-Medrol and then it went immediately bad – certainly something to ponder.